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AqualiftTM – is the most physiologic and safe among all existing implants, which can be used in any anatomic region. Nowadays AqualiftTM is the most perspective implant which soon can take the leadership and dominate in the medical market.
National Medical Technologies Center and SRMC Medicap are concerned in partnership and promotion of advanced technologies in the world market.
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Regularity of success in application of hydrophilic gel AQUALIFTTM.
With more years passing by, age-related changes occur in the human’s appearance. Wrinkles on the skin, atrophies of subcutaneous fat, hanging breasts and other withering symptoms usually take place, all due to the decreased water content in the human organism. Age-related changes of the skin develop first of all on the cell level. To comprehend the necessity of the AqualiftTM technology application, in view of the above, the basic knowledge about the skin structure and aging mechanism should be elucidated. Human skin consists of three layers – epidermis, derma and hypoderma (subcutaneous fat).Epidermis – is the upper, permanently renewing, layer of the skin. Epidermis is separated from the derma by a special structure – basal membrane. On the basal membrane there is a layer of the cells continuously dividing thus providing for the skin renewal. Division of the cells slows down with the age. At the same time thickness of epidermis decreases and the skin becomes worn-out and dull. Corneal layer of the aged skin becomes thickened (hyperkeratosis), which gives a parchment appearance to the skin. Moreover, production of lipids slows down with the age, which results in dryness of the skin and further appearance of superficial (epidermal) wrinkles. Derma takes a role of the skeleton that provides such mechanical properties for the skin as solidity, elasticity and flexibility. We can compare it with a combination of a water and spring mattresses where the collagen and elastin fibers act as “springs” and form a rigid support frame (the collagen molecules really resemble springs because their protein fibers are twisted like spirals). All space between the fibers is filled with intercellular matrix – aqueous gel which consists of mucopolysaccharides (glycosaminoglycans). Glycosaminoglycans – are big polysaccharide molecules forming in the water medium a reticular structure, its cells being able to absorb and retain a lot of water, thus creating a viscous gel that reminds kissel. Besides the fibers and intercellular matrix, derma contains cells (fibroblasts), blood vessels and glands (sweat and sebaceous). The cells main task is to synthesize and destroy the intercellular substance. This process is going on continuously, which ensures continuous renewal of the intercellular substance. Fibroblast activity decreases with the age. Especially it concerns the intercellular substance (glycosaminoglycans and supporting fibers) which looses rather quickly its ability to synthesize, whereas its destroying ability remains at the same level much longer. Collagen and elastin fibers also change their volume and quality. Elastin fibers of a young skin have mostly vertical arrangement, but after a number of years they get arranged horizontally, which leads to loss of skin elasticity. With the age, the collagen fibers become thicker and their volume and elasticity decreases. Then, there takes place accumulation of the collagen fibers being cross-linked with each other (due to various reasons), which makes them unrecognizable for the collagenase ferments, so this defective collagen goes on accumulating and gradually replace the normal fibers. As a result of change in correlation between collagens of different types, derangement of collagen matrix structure takes place, moisture content within the intercellular substance of the derma decreases, the skin looses its resilience and elasticity, then facial lines and deep (dermal) wrinkles appear. Main manifestations of the age-related changes: - Appearance of multiple wrinkles around the eyes and lips, on the neck and hands.
- Change of the facial oval (loose-hanging cheeks, deformed chin), deepened nasolabial folds.
- Increased skin dryness not improving with the help of moistening creams.
Modern conceptions of reasons for ageing: Free radicals are considered as one of the main reasons for skin ageing. A free radical – is a molecule having high reactive ability, because it has a vacant place for an electron which it tries to take away from the other molecules. When the radical gains its electron, it becomes disabled, but the other molecule, devoid of its electron (oxidized), at once becomes a radical too and begins to oxidize other molecules. Free radicals react with any biologic molecules they meet on their way – DNA, lipids, proteins. If these free radicals damage the DNA of a cell, the cell dies or becomes malignant. Damage of ferments leads to loss of their activity so they cannot any longer control chemical processes within the cell. Damage of a mitochondrion leads to energy disbalance of the cell. Damage of a cell membrane, consisting of lipids, leads to death of the cell and starts chain reaction of oxidation. Collagen molecules, damaged by the free radicals, get connected with each other forming a dimer. Collagen dimer is less elastic, that’s why accumulation of collagen dimmers leads to appearance of wrinkles. UV-radiation is another, not less important, reason of premature ageing. The role of the sunlight for the process of premature ageing is so significant that it was called as photoageing. The signs of photoaging are: thickening of the corneal layer (sun keratosis), appearance of pigmented spots, accumulation of atypical elastic fibers in the skin (elastos) and degradation of the collagen. - Destruction of the water-retaining layer.
Destruction of the water-retaining layer with water loss leads to premature fading of the skin. Epidermis receives water mainly from the derma. Water seeps into more dry upper skin layers coming from the water-saturated derma. When water reaches the dry corneal layer it tries to leave the epidermis to go into yet more dry atmosphere. Application of AqualiftTM technology allows us to save organism from premature ageing. - AqualiftTM- protects the skin from water loss, blocks damaging of the cells by stress-factors and free radicals, restores production of the collagen and elastin fibres within the injection zone, has a prolonged effect. Aesthetic shapes can be restored for a lengthy period.
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